Home » Posts tagged "上海后花园千花网"

ND brain researcher receives NFL grant

first_imgThe National Football League (NFL) will fund Notre Dame’s chemistry and biochemistry departments to research strokes and other brain injuries, professor Mayland Chang said. Chang, who has been working on the project for 15 years, studies gelatinase-based brain diseases. Funded in part by the National Institute of Health, the researched treatments are getting close to FDA trials, she said. Gelatinase is a type of enzyme that breaks down cell walls and can cause tumor metastasis in cancer, as well as problems in traumatic brain injury (TBI), strokes, aneurysms and diabetic wounds. Chang’s husband, professor Shahriar Mobashery, discovered a compound at Wayne State University called SB-3CT that could be a possible treatment for the brain diseases. Mobashery now teaches at Notre Dame. The SB-3CT compound is an inhibitor triggered by the enzyme’s reaction in the cell. Chang said a compound like SB-3CT could help stop brain damage similarly to how it helps stroke patients. The compound was synthesized more than 450 times to find a way to make it water soluble, so it can be put into an IV or given to a patient in the form of an injection, Chang said. If all goes well, the drug could be in use with stroke patients in seven to nine years, Chang said. “Would this be great to have as an injectable treatment?” she said. “It could be on the sidelines. If you get a concussion, you can get a shot. This is eventually our hope.” The current drug used to dissolve clots in ischemic, or clot-forming, stroke patients is tissue Plasminogen Activator, or tPA, Chang said. This drug dissolves the clot, but increases gelatinase enzymes, which causes hemorrhaging and brain swelling. When SB-3CT is given in tandem with this drug in experiments, it has reduced side affects. Researchers have developed an experimental model to test compounds. “We’re always looking for better ways to treat,” she said. Chang, whose son is a competitive snow boarder, witnessed the treatment for TBI when her son had a concussion last year. “If you have a concussion, they can do cognitive treatment,” she said. “They do simple things. For example, they ask you to list words that begin with the same letter. They also make you take a rest — no physical activity, nothing to rattle your brain. They don’t really do anything else.” The research team is currently searching for funding to have toxicology studies done, which will then put the drug into FDA clinical trials, Chang said. She said the team hopes the compound will improve emergency response to brain problems. “Given in an ambulance setting, it would work quickly,” she said.last_img read more

Continue reading »

Yaya Toure announces retirement from football

first_imgFormer Manchester City midfielder Yaya Toure has announced his retirement from football.The announcement was made by the Ivorian’s agent Dimitri Seluk on Friday. The 4-time African Player of the year had his contract with Greek side Olympiakos terminated in November 2018, after only three months with the club, and has been without a club since.Yaya won three Premier League titles during his time with Manchester City, scoring 79 goals in 316 appearances, in addition to two league cups and an FA Cup.He also claimed the UEFA Champions league title in 2009 with Barcelona.On the international front, Yaya captained Ivory Coast to the AFCON title 2015, their first in 23 years. He also represented his country at three FIFA World Cups from 2006 to 2014.last_img read more

Continue reading »

Raiders place Marquel Lee on I.R. to sign Dakota Allen

first_imgALAMEDA — The ankle injury sustained by Marquel Lee is serious enough to put the three-year veteran on injured reserve Tuesday, with the Raiders signing Dakota Allen off the practice squad of the Los Angeles Rams to take his place on the roster.Lee, 23, has been the fourth linebacker on the Raiders behind starters Vontaze Burfict, Tahir Whitehead and Nicholas Morrow, and a core player on special teams. He leads the Raiders with five special teams tackles. Lee, a fifth-round draft pick from …last_img read more

Continue reading »

Kick start for rugby programme

first_imgExcited children from Mabamba Primary School in southern Swaziland, after receiving an SOS Kit Aid shipment of rugby jerseys in November 2008.(Image: Swaziland Rugby) A familiar sight – Bryan Habana soars over the tryline during a Rugby World Cup game. (Image: SA Rugby) Jason Robinson (top left) and Bryan Habana (bottom left) with children at the Pimlico Academy in London. (Image: Rugby 365) John Smit, captain of the triumphant Bok rugby team, lifts the Webb Ellis Trophy. ToSmit’s left is Bryan Habana, while former president Thabo Mbeki is in the front leftof the picture. (Image: SA Rugby)Janine ErasmusRugby fans in both hemispheres are looking forward to the British and Irish Lions’ tour of South Africa in 2009. Now the tour’s main partner HSBC has launched a schools rugby initiative that includes a drive to supply underprivileged South African children with much-needed rugby equipment.The initiative, known as the Rugby Festival campaign, was launched by two of rugby’s brightest stars, England’s Jason Robinson and South Africa’s Bryan Habana. Habana was named the International Rugby Board’s (IRB) Player of the Year in 2007.The SOS Kit Aid programme is partnering with HSBC in its Rugby Festival scheme. SOS Kit Aid gives less advantaged children in emerging nations around the world a chance to play and develop rugby. It achieves this through the collection and distribution of unused or unwanted kit such as balls, jerseys, boots and protective gear, from schools around the UK and Ireland.Part of the Kit Aid programme involves, for the first time, the twinning of 40 HSBC schools in the UK with 40 South African schools. Pupils at these schools will benefit from the kit collection initiative and will be able to proceed with the development of their own programmes, with equipment delivered during the Lions tour.In November 2008 the SOS Kit Aid programme proudly announced its 100th kit delivery – to Swaziland, the first Kit Aid recipient outside eastern Europe. Rugby is a growing sport in the small Southern African nation, which currently boasts 14 clubs and 4 870 registered players. There are 1 320 pre-teen boy and 1 600 pre-teen girl players, with 946 teenage boy and 514 teenage girl players. Amongst the senior ranks there are 360 male players.Rugby stars help to grow the gameHabana and Robinson, both members of IRB Rugby World Cup-winning teams, were on hand at the twinning of the first two schools, southwest London’s Pimlico Academy and Hillcrest Primary School in Port Elizabeth.The pair kicked off the collection by donating some of their own old kit, and also took the time to offer some personal playing tips to their young fans. Over the coming months, businesses, schools and individuals in the Pimlico area will be encouraged to make their own contributions.Pimlico Academy principal Jerry Collins said, “We are delighted to be given the opportunity to twin with Hillcrest Primary in South Africa, and in so doing, participate in the SOS Kit Aid project. The opportunity to develop a wider cultural exchange with the kids in South Africa in the lead up to the Lions Tour is a hugely exciting prospect.” The school now has a rugby team for the first time ever.Robinson fully supports the programme and believes that through it, two very different cultures will be brought together in a unique way. “It offers hundreds of children both here and in South Africa a unique and fantastic way of sharing a Lions experience. I am excited to see how the twinning of the HSBC rugby schools with the schools out in South Africa will have a positive impact on the children.”South African superstar Habana personally nominated Hillcrest as the first school to be linked with an HSBC school. “Hillcrest Primary School has very basic facilities and yet they are desperate to play rugby,” he said. “Rugby is already proving to have a positive impact on the lives of these children and this will be further helped through the support of the children from Pimlico.”A superstar of rugbyHabana launched his own rugby development organisation, the Bryan Habana Foundation, earlier in 2008. “I have had a great upbringing and there was always a great level of support,” he remarked. “But you go to a school like Hillcrest where there is very little to aspire to. For me, to go there and to try to make a difference is a big challenge.”The pride of South African rugby, who plays on the wing, was an integral part of the team that lifted the William Webb Ellis Trophy for the second time in 2007. His record-equalling eight tries (the only other player to score that many tries in an IRB Rugby World Cup final is the legendary Jonah Lomu of New Zealand) earned him the IRB’s top accolade for an individual player in that year.Habana currently plays for the Pretoria-based Blue Bulls and was named the South African Player of the Year in 2005 and 2007, as well as the Young Player of the Year in 2004. The star, who famously raced a cheetah over 100m in 2007 and lost by only a narrow margin, is feared and respected by his rivals for his exceptional fleetness of foot. The cheetah race was to raise awareness of the animal’s endangered conservation status and to support the work of the De Wildt Cheetah and Wildlife Trust.As a team, South Africa is presently second on the IRB’s latest world rankings, behind their age-old rivals, the New Zealand All Blacks. The country’s Sevens Rugby team has just won their first Sevens Cup title on home soil, coming from behind to beat defending champions New Zealand 12-7 during the first week of December 2008.The tournament is the second on the annual Sevens calendar, taking place a week after the opening event of the season in Dubai – which was also won by the South Africans. The next leg of the 2008/2009 season takes place in Wellington, New Zealand in February 2009.Do you have queries or comments about this article? Email Janine Erasmus at [email protected] articlesThe other Rugby World CupUseful linksLions SA tour – official siteSouth African rugbySwaziland rugbySOS Kit AidInternational Rugby BoardIRB SevensRugby World Cup 2011De Wildt Cheetah and Wildlife Trustlast_img read more

Continue reading »

Partners for Possibility selected as finalist of the global WISE Awards

first_imgPartners for Possibility joins NGOs from Morocco and Nigeria on prestigious WISE listPartners for Possibility (PfP), a South African social enterprise that develops leadership capacity in under-resourced schools across the country, is a finalist in the global World Innovation Summit for Education (WISE) Awards.The announcement of was made this morning by the Qatar Foundation, which created the WISE Awards in 2009. Every year it evaluates hundreds of innovations in basic education before ultimately selecting six winners to be showcased at its WISE Summit in Qatar and receive $20 000 in prize money.Since its inception, the judges for the WISE Awards have evaluated over 2 400 nominations for the Awards from over 150 countries and have awarded just 54 prizes, to social innovations in countries as far afield as Finland, the USA, Spain, Morocco and India.“To be recognised by the WISE Awards is a very special achievement,” says Dr Louise van Rhyn, Founder and CEO of Partners for Possibility. “It means that our programme meets their criteria of being a creative solution to reduce inequality in South African education.”Partners for Possibility was founded in 2010 as a leadership development and principal support programme that brings together a school principal of an under-resourced school and a business leader in a year-long developmental partnership. The partnership participates in an accredited leadership development process while at the same time working together to develop solutions to the challenges faced by its specific school.Since starting at its first school in Cape Town, the programme has grown to over 720 schools across South Africa.“Our programme provides the much-needed support and leadership skills to school principals who have received little or no preparation for the challenging task of managing a complex organisation with very limited funds amidst crippling social challenges such as poverty, child-headed households, drug abuse and gangsterism.“Aside from supporting the principal and partnering him or her with a business leader who works and learns as an equal alongside them, the programme also creates fertile ground for further interventions and support from business and social change organisations,” says Van Rhyn.Partners for Possibility’s unique concept of combining leadership development with social support to principals of under-resourced schools has received wide acclaim since 2010. The global platform HR.com has selected Partners for Possibility as one of its Top International Leadership Providers in 2016 and 2017, and NGO Adviser selected PfP – the only social enterprise on its list from South Africa – as one of the top 100 NGOs in the world in 2018.“Being a WISE Finalist will also offer PfP a global platform to share its insights and solutions as well as how these could be applied to other industries and countries. We look forward to networking with other global finalists who share our passion for quality education for all children,” says Van Rhyn.It is estimated that 80% or 20 000 public schools in South Africa are “in crisis” or under-resourced and in need of support.An evaluation team from the WISE Awards will soon travel to South Africa to experience the programme first hand and to interview alumni and other key programme stakeholders. The winners are set to be announced in September 2018 during the biennial WISE Summit.“Brand South Africa is delighted to hear that Partners for Possibility have been announced as a WISE Awards Finalist.  These awards are a testament that giving back to communities does not go unrecognised”, said Brand South Africa’s GM: Stakeholder, Ms Mpumi Mabuza.last_img read more

Continue reading »

Identity Wars: Google & Yahoo! Bow to Facebook & Twitter

first_imgTop Reasons to Go With Managed WordPress Hosting Related Posts marshall kirkpatrick Why Tech Companies Need Simpler Terms of Servic… A Web Developer’s New Best Friend is the AI Wai…center_img Tags:#Analysis#news#NYT#web Yahoo! announced this morning that it is adding Facebook Connect across many of its properties. This afternoon Google Friend Connect announced the inclusion of Twitter as a top-level log-in option. These moves will be convenient for users, but may not be good for the future of the web.People have always said that Google does what’s good for the web, because what’s good for the web is good for Google. In this case I’m worried that the Royalty of the web’s last generation has crowned these two leading social networks as the Royalty of the current generation in a deal that offers traffic and money but that could suffocate the most creative developments of the open, distributed web. That could be called the web’s next generation.The Importance of IdentityIdentity is a very important matter online, particularly as everything becomes more social. Online identity is your address book, it’s your wallet, it’s your reputation and it could become a lot more. Increasingly, you take that Identity from site to site, leveraging on the next site what you did on the last one. If a particular company provides that Identity for you, it sets the rules, regulations, “interest rates” (eg. use of your info for advertising) and determines things like what parts of your identity you can use on different sites and what parts you can’t.Facebook and Twitter are becoming big Identity providers. Google and Yahoo! have wanted to be leading Identity providers themselves but today cried Uncle with a big nod to the supremacy of the two leading social networks. At this point they have an interest in doing so, because they want you to share what you do on Yahoo and Google sites with your big link-clicking network of friends on Facebook and Twitter. Google didn’t add Facebook Connect, just Twitter, because Facebook is now Google’s leading challenger.The Rest of the Identity WorldBut there are far more parties in the world of Identity than Twitter and Facebook. The Internet works because it is decentralized and there are scores of small companies, services and developers building out Identity infrastructures that are decentralized as well. Infrastructures that leverage the network-effect of the decentralized internet to provide the benefits of a large group, but are independent and interoperable in order to provide the benefits of personal freedom and control that can come from owning your own Identity.Those small players, people working on things like OpenID, ActivityStreams, the distributed social graph and other components of distributed, independent and interoperable social networking – those players may have been sold down the river by today’s deals between Yahoo and Google and Facebook and Twitter.How could that be? After all, the OpenID logo appears on the login screen for Google Friend Connect and Yahoo! has been a big supporter of OpenID. I would argue that by putting the best known brands, with the easiest log-in experiences, at the very front of the parade – Google and Yahoo have further marginalized the distributed web. The PR email to journalists about the announcement was even titled “Google Friend Connect and Twitter Get Cozy Together.” The Consequences of Today’s DealsBy choosing to favor branded log-ins and making standards-based systems an afterthought, websites using these systems are disincentivized to leverage the innovations that come from the open standards community and big Identity brands stay in control. Those websites might be Google and Yahoo! or they might be other big sites with all the more reason to favor incumbent leaders in Identity because of the support Google and Yahoo! have given them.People have talked about combining OpenID and Friend of a Friend data for spam control on blogs. “We’ll just require Facebook log-in, thanks,” I can imagine big websites saying. People are working on implementing cross-network standards for user activity data so sites can understand the activity feeds of other social networks and users of small, innovative sites can still communicate with their friends on other, larger sites. That means people will use small innovative sites and give them the support to grow. “Most people just use Facebook or Twitter,” I can imagine big websites saying. People have talked about using things like content category tags and bookmarks to build cross-site user Attention Profiles. “We’ll just look at their Facebook profiles,” I can imagine big websites saying. A distributed social web, communicating through interoperable, standards-based language, offers as much opportunity for innovation as a common tongue does for poetry, universally visible pigments do for art or cash money and free time do for a self-determined afternoon. Your clicks, your contacts, your measurable behavior and content online are like fuel to burn, cash to spend. You’ll either be able to spend that resource on things like recommendations, privileges, trust, recognition, greater efficiency and unforeseeable innovation – or those resources will be handed directly and exclusively to advertisers for the benefit of those who broker your Identity.The identity and activity payloads that come with most systems of identity don’t seem to be of much interest to sites leveraging Facebook and Twitter as primary identity providers today, though. It’s hard to think about anything else when all that potential traffic from enabling broadcast of your content is dangling in front of you.“All you little sites are interested in making it easy to do cross-site photo identification/ comment re-aggregation / book recommendation based on charecteristics of multiple social networking profiles (etc.)?” Big Website might say, “Well, Facebook and Twitter don’t do that and they are good enough for us. We’re excited about people broadcasting links to our site out to their Twitter and Facebook friends. That’s enough for us. Isn’t that innovative?”This may be more cynicism than is warranted, but I don’t think so. When dealing with hundreds of millions of peoples’ identities, the future of human communication and trillions of dollars – it’s probably good to lean a little toward cynicism when considering collaboration with incumbent industry leaders.I appreciate the ease of Facebook and Twitter login around the web as much as anyone, but every big Identity login action I take feels like an economic transaction where the change and the interest slip through my fingers and land in the pockets of Facebook and Twitter.Wouldn’t it have been better for the web to say “no, we will not simply take the easy solutions when it comes to Identity, in exchange for traffic and money. We will instead look for ways to make it easier for users of any Identity provider to engage with our websites.” The short-term trade of giving more control to two big social networks, in exchange for traffic and ad money, may not serve anyone well in the long run. 8 Best WordPress Hosting Solutions on the Marketlast_img read more

Continue reading »

Small restaurant owners oppose ban on styrofoam food containers

first_img Sasha Foo, 00:00 00:00 spaceplay / pause qunload | stop ffullscreenshift + ←→slower / faster ↑↓volume mmute ←→seek  . seek to previous 12… 6 seek to 10%, 20% … 60% XColor SettingsAaAaAaAaTextBackgroundOpacity SettingsTextOpaqueSemi-TransparentBackgroundSemi-TransparentOpaqueTransparentFont SettingsSize||TypeSerif MonospaceSerifSans Serif MonospaceSans SerifCasualCursiveSmallCapsResetSave SettingsSAN DIEGO (KUSI)- A proposal to ban styrofoam products in the City of San Diego is heading for a final vote next month.On Thursday, restaurant owners who oppose the measure held a news conference in Logan Heights to explain how a ban would hurt them. Restaurant owners like Javier Rodriguez said if the city enacts a ban on polystyrene or styrofoam containers, the cost of switching to a more expensive paper product will have to passed on to customers.Rodriguez and other small restaurant owners said they don’t have the budgets of bigger corporate run restaurants and paying more for the alternative containers would mean making cuts in other areas.“If we get more expenses, we have to cut the labor, we have to cut the hours. It’s not fair for them or for us, too,” Rodriguez said.A study commissioned by the California Restaurant Association looked at the cost of food containers sold in the Los Angeles area. The study found that a 9 inch hinged container made of styrofoam would cost about 10 cents, yet a compostable paper product of the same kind would be around 24 cents, amounting to a 145% increase.There’s a different view of the proposed ban at Ponce’s, a family owned Mexican restaurant in Kensington and now in a second location in Del Sur.The director of operations, Mikey Knab said Ponce’s switched to compostable paper containers about a year and a half ago.Knab said the price difference was a nickel or less and the restaurant did not have to raise its food prices. He said the restaurant was willing to bear the extra cost so that future generations would not be stuck with the cost of an unhealthy planet.“By allowing that plastic into the food system, you’re making everyone else in the world pay that cost, rather than people who are choosing it. So, yes, we could choose not to patronize restaurants that use styrofoam, but that wouldn’t let us choose the fish that come out of the ocean to have that.” Knab said.The proposed ordinance would give small businesses with less than $500,000 in annual sales, a two year period to comply. The city would also allow business owners to ask for a “hardship” exemption to extend that deadline even further.Larger businesses would have to start following the ordinance in 90 days. The San Diego City Council is scheduled to take a final vote on the styrofoam ban on January 8. Posted: December 20, 2018 December 20, 2018 Sasha Foo Small restaurant owners oppose ban on styrofoam food containers Categories: Local San Diego News FacebookTwitterlast_img read more

Continue reading »