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Thyroid drug ‘boosts risk of fractures in the elderly’

first_img Share Share HealthLifestyle Thyroid drug ‘boosts risk of fractures in the elderly’ by: – April 29, 2011 Sharing is caring! Sharecenter_img 19 Views   no discussions Tweet The butterfly-shaped thyroid gland produces the hormone thyroxineMany elderly people may be taking “excessive” medication for their thyroid problems, increasing their fracture risk, researchers warn.A synthetic hormone, thyroxine, is given to people whose thyroid glands produce too little naturally.But writing in the British Medical Journal, researchers say having too much boosts fracture risk and doses may need to be reduced as people age.A British expert said there was not enough research into the condition.It has been estimated that 20% of older people are on long-term treatment for an underactive thyroid (hypothyroidism).Patients are supposed to be checked regularly to ensure they are on the right dose, but for many it often remains unchanged into old age.This can lead to people developing the opposite problem, an over-active thyroid – caused by having too much thyroxine – which can increase the risk of fractures, particularly in older women.In this study, a team from the Women’s College Research Institute in Toronto looked at 213,500 people aged 70 and over who had received at least one prescription for levothyroxine – the synthetic version of thyroxine – between 2002 and 2007.‘Unexpectedly low’Participants were grouped into people who were currently on the medication, those who had stopped taking it between 15 and 180 days prior to study and those who had stopped taking it more than 180 days prior.Just over 10% – 22,236 people – had had at least one fracture during the study period.Those who were currently taking thyroxine, or who had recently stopped were at a significantly higher risk of experiencing fractures.Writing in the BMJ, the researchers led by Dr Lorraine Lipscombe, said it suggested medication levels should be more closely monitored “in this vulnerable population”.In the same journal, Professor Graham Leese at Ninewells Hospital in Dundee, said ideal thyroxine doses may vary with age and be “unexpectedly low” in elderly people.“It is 120 years since the effect of excess thyroid hormone on bone was first described, yet research in this area still lacks funding,” he said.“With the prevalence of treated hypothyroidism increasing, and the annual economic burden of fractures in the United Kingdom currently estimated at £5.1bn ($8.4bn), such research warrants a higher priority.”BBC Newslast_img read more

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first_imgFROM NEIL DOHERTY: NEIL Lennon basked in the glory of Celtic’s Champions League success and then declared he wouldn’t minding basking in some sunshine….in Malaga!FC Malaga are one of the other 16 teams joining Celtic in the knock-out stages of the tournament after Celtic’s win over Spartak Moscow at Paradise.Lennon said he wouldn’t say no to a Battle of Britain clash with Man United. Then he joked: “I would take Malaga – it would be nice this time of the year over there!”He went on: “It means the world to me as a young manager in my first year in the Champions League to qualify with 10 points, I am very proud of the players, they have performed a miracle.“People laughed at me when I said at the start that my target was to qualify.“No one gave us a prayer going into this group but we have qualified and deservedly so. I think you could see the players progressing last year. “We have some really talented players who I felt could play at European level.“I didn’t want them just to be remembered for beating Barcelona but we have beaten Barcelona and qualified for the last-16 and that is a fantastic feather to have in your cap.”“Seriously, it is going to be really tough, against the top teams in the groups.“You just don’t know what shape teams are going to be in two or three months’ time. But we are there, we are going to enjoy it and we want to progress as far as we can in the competition.“Who knows where it can take you? “The spirit is fantastic, we have some quality players, they have put everything into the group and they have grown as the campaign has gone on and some of them have enhanced their reputations no end.“The draw is on the 20th and it is something that we look forward to, I just want them to concentrate on domestic duties now.”Lennon was seen hiding in the dug-out when Commons stepped up to score the winner.“I didn’t watch it, I turned my back on it,” said the Armagh man. “I’d seen the last couple of penalties and we missed them. I saw Gary Parker (coach) turn his back and so I thought I would wait until the roar goes up.“Kris showed great mental strength to take it, I’m sure he was aware of the significance of the penalty but I thought he had a fantastic game.Spartak caretaker coach Valery Karpin was magnanimous in defeat.He said: “I would like to congratulate Celtic, they deserved it because they have had a very good Champions League campaign.“The referee blew his whistle for a penalty so it was a penalty.“The first half was the probably the best we have played in a long time, so it is disappointing to lose matches when you play well.“In the second half the three midfielders who were supporting the striker were not so influential.“But I cannot blame any of our players, I have to thank them and the fans who came to Glasgow to support us when the game did not mean anything to us.”THE HOOPS REPORT: ANYONE FANCY A TRIP TO MALAGA? ASKS HAPPY HOOP LENNON was last modified: December 5th, 2012 by BrendaShare this:Click to share on Facebook (Opens in new window)Click to share on Twitter (Opens in new window)Click to share on LinkedIn (Opens in new window)Click to share on Reddit (Opens in new window)Click to share on Pocket (Opens in new window)Click to share on Telegram (Opens in new window)Click to share on WhatsApp (Opens in new window)Click to share on Skype (Opens in new window)Click to print (Opens in new window)Tags:THE HOOPS REPORT: ANYONE FANCY A TRIP TO MALAGA? ASK HAPPY HOOP LENNONlast_img read more

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